Endocrine Abstracts

Introduction: Acromegaly – a serious debilitating disease resulting in decreased quality and length of life. Due to the late nature of the diagnosis, the lack of prospects for a surgical or non-radical adenomectomy leads to a somatostatin analogues (SA) treatment as primary or secondary therapy, which is a long-term, sometimes lifelong. Therefore, the question of tolerability and prevention of life-threatening complications for these patients is very important. Since the ...

A role of autoimmune aggression is postulated in the pathogenesis of different diseases in endocrinology. Forty to sixty percent of cases of central diabetes insipidus (CDI) are considered to be idiopathic. Primary polydipsy is a diagnosis of an exclusion of diabetes insipidus on the basis of water deprivation test, but sometimes it precedes the overt CDI. Thus the aim of this study was to define the prevalence of pituitary autoantibodies in patients with CDI and primary polyd...